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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0190 | D-Xylulose | Others , Endogenous Metabolite | |
D-Xylulose is converted from xylitol by the enzyme NAD+-linked xylitol dehydrogenase in the glucuronate pathway, the most important xylitol-handling metabolic pathway in mammals. | |||
T83885 | DXR Inhibitor 11a sodium | 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a | |
DXR inhibitor 11a, with an IC50 value of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum's growth in isol... | |||
T83908 | DXR Inhibitor 11a (free acid) | 1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a | |
DXR inhibitor 11a, with an IC50 of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also hampers the growth of P. falciparum in isolated human erythrocytes, demonstrat... | |||
T37988 | D-Ribulose-5-phosphate (sodium salt) | Ru5P,D-Ribulose-5-phosphate (sodium salt) | |
D-Ribulose-5-phosphate is an intermediate in the pentose phosphate pathway. [1][2] It can be derived from 6-phosphogluconate by a dehydrogenase or from xylulose 5-phosphate by ribulose phosphate 3-epimerase. D-Ribulose-5... | |||
T78936 | Antimalarial agent 27 | Parasite | |
Antimalarial agent 27 (compound 11a) potently inhibits P. falciparum with an IC50 of 0.37 μM and targets the parasite's 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme with an IC50 of 0.11 μM, indicating its... |